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Home > Products > New Drugs & Specific Medicine > Supply Pharmaceutical Raw Material CAS 74863-84-6 Argatroban Intermediate

Supply Pharmaceutical Raw Material CAS 74863-84-6 Argatroban Intermediate

Basic Info

Model No.: Argatroban powder

Product Description

  Product Description    Specifications Supply Pharmaceutical Raw Material CAS 74863-84-6  Argatroban Intermediate  1.Best price and good service
2.Offer Documents(GMP,DMF,COA)
3.Prompt shipment
4.Antihypertensive Drugs     Medical uses Argatroban is an anticoagulant that is a small molecule direct thrombin inhibitor. In 2000, argatroban was licensed by the Food and Drug Administration (FDA) for prophylaxis or treatment of thrombosis in patients with heparin-induced thrombocytopenia  (HIT). In 2002, it was approved for use during percutaneous coronary interventions in patients who have HIT or are at risk for developing it. In 2012, it was approved by the MHRA in the UK for anticoagulation in patients with Heparin-Induced Thrombocytopenia Type II (HIT) who require parenteral antithrombotic therapy. Argatroban is given intravenously and drug plasma concentrations reach steady state in 1-3 hours.Argatroban is metabolized in the liver and has ahalf-life of about 50 minutes. It is monitored by PTT. Because of its hepatic metabolism, it may be used in patients with renal dysfunction. (This is in contrast to lepirudin, a direct thrombin inhibitor that is primarily renally cleared).  

Argatroban

  

Systematic (IUPAC) name

(2R,4R)-1-[(2S)-5-(diaminomethylideneamino)-2-[[(3R)-3-methyl-1,2,3,4-tetrahydroquinolin-8-yl]sulfonylamino]pentanoyl]-4-methyl-piperidine-2-
carboxylic acid

Pharmacokinetic data

Bioavailability

100% (intravenous)

Protein binding

54%

Metabolism

hepatic

Half-life

39 and 51 minutes

Identifiers

CAS number

74863-84-6

Chemical data

Formula 

C23H36N6O5S 

Mol. mass

508.635 g/mol

        Packaging & Shipping   Argatroban  powder         Argatroban  powder  Samples   Packaging Detail:    25kg/drum   MOQ: 1 Drum   Delivery Time: 3-7 days after receipt of payment         Argatroban  Package      Our Services Arshine-----Your Always Trusted Pharma Brand     We have more than 450 vendors, Arshine could save your effort to serve customers with  supplying all your needs!   Why choose Arshine? 1. We has 8 years’ exporting experience in active pharmaceutical ingredient products.  Our professionaland thoughtful after-sales service eliminates your worries. 2.We can provide you with thousands of products of different levels. 3. We offer convenient one-station purchasing service.   Our team:     Company Information Arshine is one of the professional suppliers for pharmaceutical raw materials for more than 12 years in China.  Offer Original COA, MOA, GMP, sample and Other need documents (to support the registration if you need).  Vendors:  NCPC,CSPC, Guo Bang, Zhuhai United, Lv Yuan, Ningxia duowei, Hebei Yu Xing, Jin Xing, Jiheng, Kun Shan, Fengyuan, Jian Ming, XiongDi, Hebei dongfeng etc.    Our Family   Global Pharma Fairs   FAQ 1. How long have your company run on active pharmaceutical ingredients? 12 years focusing on pharma field,8 years exporting experience.   2. Which payment terms are you accept? Payment term: L/C   D/A   D/P   T/T   Western Union   MoneyGram   3. After an order is placed, when to deliver? It depends on whether the products you buy has inventory. If we have inventory, generally we can arrange shipment after receipt of payment 2 to 3 days. If not, it will be decided by the time of the factory production.   4. How about your company's certification? GMP, FDA, EP, BP etc.               

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Product Categories : New Drugs & Specific Medicine